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Caffeine Anhydrous Natural B.P. / E.P. / FCC / J.P. / U.S.P.

NAME	Caffeine Anhydrous Natural B.P. / E.P./ FCC / J.P. / U.S.P.
CHEMICAL FORMULA	C₈H₁₀N₄O₂	Molecular Weight: 194.2
CAS NUMBER	58-08-02
USE	CNS stimulant/ diuretic/ cardiac & respiratory stimulant.
DESCRIPTION	A white crystalline powder or silky, white crystals.
CHEMICAL SPECIFICATION	TESTS	SPECIFICATIONS
	Solubility	Sparingly soluble in water, freely souble in boining water, slightly soluble in ethanol and in ether. It dissolves in concetrated solution of alkali benzoates or salicylates.
	Identification	To Comply.
	Related Substances	Any spot in the chromatogram obtained with the test solution, apart form the principal spot, is not more intense than the spot in the chromatogram obtained with the reference solution (0.5 %).
	Sulphate	NMT 500 ppm.
	Heavy Metals	NMT 10 ppm.
	Loss on drying	NMT 0.5 %
	Sulphated ash	NMT 0.1 %
	Organic Volatile impurities	To Comply.
	Assay	98.5 % to 101 % of C₈H₁₀N₄O₂ on dried basis.
PACKAGING	25 Kgs Blue HDPE Drum.
STORAGE	Store in cool, dry place in well-closed containers.

NAME	L-Lysine Monohydrochloride U.S.P.
CHEMICAL FORMULA	C₆H₁₄N₂O₂Hc1	Mol. Weight 182.70
CAS NUMBER	657-27-2
USE	Amino acid.
DESCRIPTION	White odourless powder.
CHEMICAL SPECIFICATION	TESTS	SPECIFICATIONS
	Solubility	Freely soluble in water.
	Identification	+ve
	Sp. Optical rotaion	+20.4° to 21.4°
	Loss on drying	NMT 0.4 %
	Residue on ignition	NMT 0.1 %
	Sulphates	NMT 0.03 %
	Iron	NMT 0.003 %
	Heavy Metals	NMT 0.0015 %
	Organic Volatile Impurities	To copmly U.S.P.
	Chloride content	Between 19.0 % and 19.6 %
	Arsenic	NMT 1.5 ppm.
	Assay	Between 98.5 % and 101.5 % on dried basis.
PACKAGING	25 Kgs Blue HDPE Drum.
STORAGE	Store in cool, dry place in well-closed containers.
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